Common name: Ivermectin

Chemical name: 22, 23-dihydro Avermectin B1

Origin: It is the hydrogenation product of Avermectin B1a and B1b.

Formula and molecular weight
H2B1a: C48H74O14=875.1
H2B1b: C47H72O14=861.

Properties:
Melting point: 157-162C

Solubility in water and organic solvents:
Easily soluble in toluene, ethyl acetate, ethanol, methanol and the like, its solubility in water is very low (10¦Ìg/L).

Toxicity:
Acute oral LD50 in rats: 94.3~212.0mg/kg; 102.7~194.8mg/kg
Acute dermal LD50 in rats: 1886.6~4420.4mg/kg; 1461.0~3451.0mg/kg

Use
The product is an antibiotic agent, which is active against nematodes, insects and mites. Injection and tablet made from the product are active against gastrointestinal nematodes, hyproderma bovis, hyproderma lineatum, sheep nose bot, psoroptes ovis, sarcoptes scabiei var suis, sarcoptes ovis and the like, In addition, it is indicated for the treatment of endoparasites (nematodes such as rondworms and lungworms). The product may be formulated as an insecticide and miticide used in agriculture, which is efficacious against mites, diamondback worm, common cabbage worm, leafminers, psylla, nematodes and the like. Its main characteristics are as follows: It is efficacious against endo- and ecto-parasites only used once.

Storage
Sealed tightly and stored away from light in a cool and dry place.

Specifications:
EP, USP.